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If you are travelling by tube, John Street is easily walkable from either Russell Square or Chancery Lane station. If you are travelling by overground, the nearest stations are Euston and Kings Cross.
Directions from Kings Cross station: Catch a number 46 bus, towards Stonecutter Street, or a number 45 bus towards Clarence Avenue/Poynders Road. Both buses will take you to the end of Northington Street.
Directions from Euston: Catch a number 59 bus, towards Streatham Hill/Telford Avenue, or a number 68 bus towards West Norwood Bus Garage. Both buses will take you to Russell Square.